Clinical TrialID 5193
Phenethyl Isothiocyanate in Preventing Lung Cancer in Smokers
NCT00691132
Lung Cancer|Tobacco Use Disorder
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Record Fields
Scalar fields from the final clinical_trial record.
- Clinical Trial Id
- 5193
- Evidence Id
- 5193
- Core Evidence Id
- 5193
- Source Clinical Trial Id
- 5175
- Herb2 Clinical Trial Id
- HBCT005175
- Nct Id
- NCT00691132
- Title
- Phenethyl Isothiocyanate in Preventing Lung Cancer in Smokers
- Status
- Completed
- Phase
- Phase 2
- Study Result
- Yes
- Study Condition
- Lung Cancer|Tobacco Use Disorder
- Study Type
- Interventional
- Study Design
- Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
- Intervention
- DRUG: phenethyl isothiocyanate|OTHER: placebo
- Intervention Allocation
- Randomized
- Intervention Model
- Crossover
- Intervention Mask
- Double
- Intervention Purpose
- Prevention
- Gender
- All
- Age
- Adult, Older_Adult
- Enrollment
- 107
- Outcome Measure
- Urinary Levels of Biomarkers of NNK Metabolism, Urinary levels of Total ITC and PEITC-NAC by treatment sequence groups and treatment period., 2 periods, 5 days each on PEITC or Placebo, with washout week between|Urinary Levels of Biomarkers of NNK Metabolism, The ratio of urinary \[pyridine-D4\]hydroxy acid : total \[pyridine-D4\]NNAL will be measured. This ratio is not expected to be influenced by the number of cigarettes smoked per day, or smoking topography., After 5 days of treatment
- Sponsor Collaborator
- University of Minnesota|National Cancer Institute (NCI)
- Funded By
- OTHER
- Location
- Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, 55455, United States
- Other Id
- 2007NT127|R01CA122244|0712M22651
- Start Date
- 2009-02
- Primary Completion Date
- 2013-01
- Completion Date
- 2013-01
- First Posted
- 2008-06-05
- Results First Posted
- 2017-04-04
- Last Update Posted
- 2017-05-12
- Study Document
- Study Url
- https://clinicaltrials.gov/study/NCT00691132
- Title Cn
- Title En
- Phenethyl Isothiocyanate in Preventing Lung Cancer in Smokers
- Bilingual Status
- semi_complete