Clinical TrialID 4964
Effects on Cardiovascular Risk Factors of the Endogenous Hydroxytyrosol Generation After the Combined Intake of Wine and Tyrosol in Humans
NCT02783989
Cardiovascular Disease
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Record Fields
Scalar fields from the final clinical_trial record.
- Clinical Trial Id
- 4964
- Evidence Id
- 4964
- Core Evidence Id
- 4964
- Source Clinical Trial Id
- 4944
- Herb2 Clinical Trial Id
- HBCT004944
- Nct Id
- NCT02783989
- Title
- Effects on Cardiovascular Risk Factors of the Endogenous Hydroxytyrosol Generation After the Combined Intake of Wine and Tyrosol in Humans
- Status
- Completed
- Phase
- Study Result
- No
- Study Condition
- Cardiovascular Disease
- Study Type
- Interventional
- Study Design
- Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
- Intervention
- OTHER: white wine|DIETARY_SUPPLEMENT: tyrosol
- Intervention Allocation
- Randomized
- Intervention Model
- Crossover
- Intervention Mask
- Intervention Purpose
- Basic_Science
- Gender
- All
- Age
- Adult, Older_Adult
- Enrollment
- 33
- Outcome Measure
- Metabolic: changes in hydroxytyrosol generation, Hydroxytyrosol generation from tyrosol ingestion in urine (24 hours urine collection), change from baseline at 4 weeks|Vascular effects: changes in endothelial function, It will be measured in the morning by monitoring endothelium-mediated changes in the digital pulse waveform, known as the Peripheral Arterial Tone (PAT) signal., change from baseline at 4 weeks|Metabolic effects (n=12), Additionally, 12 participants will be asked to collect a 24-hour urine specimen at two intervals (0-8 h and 8-24 h) the first day of each intervention, following the treatment ingestion (n=12)., up to 24 hours
- Sponsor Collaborator
- Parc de Salut Mar
- Funded By
- OTHER
- Location
- IMIM (Hospital del Mar Medical Research Institute), Barcelona, 08003, Spain
- Other Id
- IMIMFTCLFT/DOPET/3
- Start Date
- 2016-01-20
- Primary Completion Date
- 2018-06-25
- Completion Date
- 2018-06-25
- First Posted
- 2016-05-26
- Results First Posted
- Last Update Posted
- 2019-05-07
- Study Document
- Study Url
- https://clinicaltrials.gov/study/NCT02783989
- Title Cn
- Title En
- Effects on Cardiovascular Risk Factors of the Endogenous Hydroxytyrosol Generation After the Combined Intake of Wine and Tyrosol in Humans
- Bilingual Status
- semi_complete