Clinical TrialID 387

A Study of Phyllanthus Niruri and Sida Cordifolia in Diabetic Peripheral Polyneuropathy

NCT02107469

Diabetic Polyneuropathy|Diabetic Neuralgia|Diabetic Neuropathies|Diabetic Neuropathy

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Record Fields

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Clinical Trial Id
387
Evidence Id
387
Core Evidence Id
387
Source Clinical Trial Id
373
Herb2 Clinical Trial Id
HBCT000373
Nct Id
NCT02107469
Title
A Study of Phyllanthus Niruri and Sida Cordifolia in Diabetic Peripheral Polyneuropathy
Status
Completed
Phase
Study Result
No
Study Condition
Diabetic Polyneuropathy|Diabetic Neuralgia|Diabetic Neuropathies|Diabetic Neuropathy
Study Type
Interventional
Study Design
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Intervention
DRUG: Sida cordifolia roots|DRUG: Phyllanthus niruri|DRUG: Sida cordifolia roots extract|DRUG: Phyllanthus niruri extract|OTHER: Sida cordifolia placebo|OTHER: Phyllanthus niruri placebo
Intervention Allocation
Randomized
Intervention Model
Parallel
Intervention Mask
Quadruple
Intervention Purpose
Treatment
Gender
All
Age
Adult, Older_Adult
Enrollment
98
Outcome Measure
Improvement of NTSS-6 SCORE in per cent from baseline, Validated symptom score containing 6 questions investigation severity (not present, mild, moderate, severe) and frequency (never or occasional, occasional but normal, often, almost continuous) of symptoms (aching pain, allodynia, burning pain, lancinating pain, numbness, prickling sensation)., Initially, after 1, 2, 3, 5, 8 weeks of treatment, where placebo group will start again in one of the herbal treatment groups after 3 weeks (9 instead of 6 assessments)
Sponsor Collaborator
Rosenberg European Academy of Ayurveda|EUROPEAN PROFESSIONAL ASSOCIATION OF AYURVEDA PRACTITIONERS AND THERAPISTS
Funded By
OTHER
Location
P.D. Patel Ayurveda Hospital, Nadiad, Gujarat, 387001, India
Other Id
NADIAD 2014
Start Date
2014-06
Primary Completion Date
2016-02
Completion Date
2016-02
First Posted
2014-04-08
Results First Posted
Last Update Posted
2016-02-24
Study Document
Study Url
https://clinicaltrials.gov/study/NCT02107469
Title Cn
Title En
A Study of Phyllanthus Niruri and Sida Cordifolia in Diabetic Peripheral Polyneuropathy
Bilingual Status
semi_complete