Clinical TrialID 3771

The Effects of Supplementing Tyrosine on Blood Pressure in Parkinson's Disease

NCT01676103

Parkinson's Disease

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Record Fields

Scalar fields from the final clinical_trial record.

Clinical Trial Id
3771
Evidence Id
3771
Core Evidence Id
3771
Source Clinical Trial Id
3745
Herb2 Clinical Trial Id
HBCT003745
Nct Id
NCT01676103
Title
The Effects of Supplementing Tyrosine on Blood Pressure in Parkinson's Disease
Status
Completed
Phase
Phase 1|Phase 2
Study Result
No
Study Condition
Parkinson's Disease
Study Type
Interventional
Study Design
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Intervention
DIETARY_SUPPLEMENT: Tyrosine|OTHER: Placebo Comparator:Sugar Pill
Intervention Allocation
Randomized
Intervention Model
Parallel
Intervention Mask
Double
Intervention Purpose
Treatment
Gender
All
Age
Adult, Older_Adult
Enrollment
40
Outcome Measure
Determine the effects of tyrosine supplementation on orthostatic hypotension in people with PD, Orthostatic Blood Pressure Testing: Subjects will sit and rest for 10 minutes. Blood pressure will be taken in this resting position after the 10 minutes. Subjects will then stand upright for 3 minutes. Blood pressure will be taken every minute for those 3 minutes. A drop in systolic BP of 20 mmHg and a 10 mmHg in diastolic drop within these 3 minutes indicates orthostatic hypotension according to the American Academy of Neurology. Blood Samples: Norepinephrine and tyrosine will all be examined via blood samples drawn by a medical assistant or physician from the forearm vein in vacutainer tubes. Two vacutainers of three cc's of blood will be collected and frozen until analyzed., 7 days
Sponsor Collaborator
New York Institute of Technology|Michael J. Fox Foundation for Parkinson's Research
Funded By
OTHER
Location
New York Institue of Technology, Old Westbury, New York, 11568-8000, United States
Other Id
BHS-797
Start Date
2012-09
Primary Completion Date
2013-11
Completion Date
2013-11
First Posted
2012-08-30
Results First Posted
Last Update Posted
2014-04-16
Study Document
Study Url
https://clinicaltrials.gov/study/NCT01676103
Title Cn
Title En
The Effects of Supplementing Tyrosine on Blood Pressure in Parkinson's Disease
Bilingual Status
semi_complete