Clinical TrialID 3746

Evaluation of Efficacy and Safety of add-on Sarcosine in Patients With Major Depressive Disorder

NCT04975100

Major Depressive Disorder

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Record Fields

Scalar fields from the final clinical_trial record.

Clinical Trial Id
3746
Evidence Id
3746
Core Evidence Id
3746
Source Clinical Trial Id
3719
Herb2 Clinical Trial Id
HBCT003719
Nct Id
NCT04975100
Title
Evaluation of Efficacy and Safety of add-on Sarcosine in Patients With Major Depressive Disorder
Status
Completed
Phase
Phase 4
Study Result
No
Study Condition
Major Depressive Disorder
Study Type
Interventional
Study Design
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Intervention
DRUG: Sarcosine and SSRI|DRUG: Placebo and SSRI
Intervention Allocation
Randomized
Intervention Model
Parallel
Intervention Mask
Double
Intervention Purpose
Treatment
Gender
All
Age
Adult, Older_Adult
Enrollment
60
Outcome Measure
Change in severity of depressive symptoms from baseline., The change in symptoms of depression will be evaluated using Montgomery Asberg Depression Rating Scale score. Each item of the questionnaire yields a score of 0 to 6. The overall score ranges from 0 to 60. A higher score indicates more severe depression., 8 weeks
Sponsor Collaborator
All India Institute of Medical Sciences, Bhubaneswar
Funded By
OTHER
Location
AIIMS, Bhubaneswar, Odisha, 751019, India
Other Id
IEC/AIIMSBBSR/PGThesis/21/07
Start Date
2021-08-26
Primary Completion Date
2023-04-30
Completion Date
2023-04-30
First Posted
2021-07-23
Results First Posted
Last Update Posted
2023-07-25
Study Document
Study Url
https://clinicaltrials.gov/study/NCT04975100
Title Cn
Title En
Evaluation of Efficacy and Safety of add-on Sarcosine in Patients With Major Depressive Disorder
Bilingual Status
semi_complete