Clinical TrialID 2573
Efficacy and Safety of Using Combination of 755-nm Picosecond Alexandrite Laser and 2% Hydroquinone Compared With 2% Hydroquinone Alone for the Treatment of Melasma: a Randomized Split-face Controlled Trial
NCT04597203
Melasma
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Record Fields
Scalar fields from the final clinical_trial record.
- Clinical Trial Id
- 2573
- Evidence Id
- 2573
- Core Evidence Id
- 2573
- Source Clinical Trial Id
- 2552
- Herb2 Clinical Trial Id
- HBCT002552
- Nct Id
- NCT04597203
- Title
- Efficacy and Safety of Using Combination of 755-nm Picosecond Alexandrite Laser and 2% Hydroquinone Compared With 2% Hydroquinone Alone for the Treatment of Melasma: a Randomized Split-face Controlled Trial
- Status
- Phase
- Study Result
- No
- Study Condition
- Melasma
- Study Type
- Interventional
- Study Design
- Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
- Intervention
- DEVICE: 755-nm picosecond alexandrite laser with topical 2% hydroquinone|DRUG: topical 2% hydroquinone
- Intervention Allocation
- Randomized
- Intervention Model
- Parallel
- Intervention Mask
- Double
- Intervention Purpose
- Treatment
- Gender
- All
- Age
- Adult
- Enrollment
- 20
- Outcome Measure
- Modified melasma area and severity index score(mMASI) - comparing between Picosecond laser 755 nm with 2%HQ and 2%HQ alone for treatment of melasma of using combination of 755-nm picosecond alexandrite laser and 2% hydroquinone, score range 0-24, 6 months|Melanin index measured by Mexameter® - comparing between Picosecond laser 755 nm with 2%HQ and 2%HQ alone for treatment of melasma, measuring in au, 6 months|Average melanin measured by Antera3D® - comparing between Picosecond laser 755 nm with 2%HQ and 2%HQ alone for treatment of melasma, measuring in au, 6 months|Patient satisfaction quartile score - comparing between Picosecond laser 755 nm with 2%HQ and 2%HQ alone for treatment of melasma, score 0 -100%, 6 months|Physician evaluation quartile score - comparing between Picosecond laser 755 nm with 2%HQ and 2%HQ alone for treatment of melasma, score 0 -100%, 6 months
- Sponsor Collaborator
- Mahidol University
- Funded By
- OTHER
- Location
- Department of Dermatology, Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand
- Other Id
- si 082/2019
- Start Date
- 2020-10
- Primary Completion Date
- 2021-01
- Completion Date
- 2021-02
- First Posted
- 2020-10-22
- Results First Posted
- Last Update Posted
- 2020-10-23
- Study Document
- Study Url
- https://clinicaltrials.gov/study/NCT04597203
- Title Cn
- Title En
- Efficacy and Safety of Using Combination of 755-nm Picosecond Alexandrite Laser and 2% Hydroquinone Compared With 2% Hydroquinone Alone for the Treatment of Melasma: a Randomized Split-face Controlled Trial
- Bilingual Status
- semi_complete