Clinical TrialID 2570

Comparison of Topical Silymarin With Hydroquinone in the Treatment of Melasma

NCT03982849

Melasma

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Record Fields

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Clinical Trial Id
2570
Evidence Id
2570
Core Evidence Id
2570
Source Clinical Trial Id
2549
Herb2 Clinical Trial Id
HBCT002549
Nct Id
NCT03982849
Title
Comparison of Topical Silymarin With Hydroquinone in the Treatment of Melasma
Status
Completed
Phase
Phase 2
Study Result
No
Study Condition
Melasma
Study Type
Interventional
Study Design
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Intervention
DRUG: Hydroquinone 4% Cream|DRUG: silymarin 0.7% cream
Intervention Allocation
Randomized
Intervention Model
Parallel
Intervention Mask
Single
Intervention Purpose
Treatment
Gender
Female
Age
Adult
Enrollment
92
Outcome Measure
Therapeutic response will be assessed in terms of percent reduction in MASI score from baseline to 1,2 and 3 month of treatment course and for next 3 months of follow up., * \>75% improvement as excellent * 50-75% improvement as good * 25-50% improvement as medium * \< 25% improvement as poor, 6 months
Sponsor Collaborator
Islamabad Medical and Dental College
Funded By
OTHER
Location
Islamabad medical and Dental College, Islamabad, Federal, 44000, Pakistan
Other Id
IMDC
Start Date
2019-07-15
Primary Completion Date
2019-12-31
Completion Date
2020-01-15
First Posted
2019-06-12
Results First Posted
Last Update Posted
2020-02-12
Study Document
Study Url
https://clinicaltrials.gov/study/NCT03982849
Title Cn
Title En
Comparison of Topical Silymarin With Hydroquinone in the Treatment of Melasma
Bilingual Status
semi_complete