Clinical TrialID 2389

Bioavailability of Diosmin/Hesperidin (90/10) 500 mg Tablets With Regards to Reference Product

NCT05158192

Bioequivalence

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Trial: 1Ingredient: 1Links: 1
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Record Fields

Scalar fields from the final clinical_trial record.

Clinical Trial Id
2389
Evidence Id
2389
Core Evidence Id
2389
Source Clinical Trial Id
2366
Herb2 Clinical Trial Id
HBCT002366
Nct Id
NCT05158192
Title
Bioavailability of Diosmin/Hesperidin (90/10) 500 mg Tablets With Regards to Reference Product
Status
Completed
Phase
Phase 1
Study Result
No
Study Condition
Bioequivalence
Study Type
Interventional
Study Design
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Intervention
DRUG: Diosmin/Hesperidin (90/10) 500 mg Test Drug|DRUG: Diosmin/Hesperidin (90/10) 500 mg Reference Product
Intervention Allocation
Randomized
Intervention Model
Crossover
Intervention Mask
Intervention Purpose
Basic_Science
Gender
All
Age
Adult
Enrollment
12
Outcome Measure
Total Diosmin/Hesperidin (90/10): area under the plasma concentration-time curve from 0 to 72 hours (AUC0-72), 23 samples up to 72 hours will be taken after the administration in each period., From tablet intake and up to 72 hours after tablet intake|Total Diosmin/Hesperidin (90/10): area under the plasma concentration-time curve from 0 to t hours (AUC0-t), 23 samples up to 72 hours will be taken after the administration in each period., From tablet intake and up to 72 hours after tablet intake|Total Diosmin/Hesperidin (90/10): Maximum plasma concentration (Cmax), 23 samples up to 72 hours will be taken after the administration in each period., From tablet intake and up to 72 hours after tablet intake
Sponsor Collaborator
Laboratorios Andromaco S.A.
Funded By
INDUSTRY
Location
Azidus Laboratories Ltd., Chennai, Tamil Nadu, 600048, India
Other Id
HP8834-01
Start Date
2021-11-04
Primary Completion Date
2021-12-14
Completion Date
2021-12-14
First Posted
2021-12-15
Results First Posted
Last Update Posted
2022-02-14
Study Document
Study Url
https://clinicaltrials.gov/study/NCT05158192
Title Cn
Title En
Bioavailability of Diosmin/Hesperidin (90/10) 500 mg Tablets With Regards to Reference Product
Bilingual Status
semi_complete