Clinical TrialID 1894
Effects of Octanoic Acid for Treatment of Essential Voice Tremor
NCT01864525
Essential Voice Tremor|Vocal Tremor|Voice Tremor|Essential Tremor of Voice
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Record Fields
Scalar fields from the final clinical_trial record.
- Clinical Trial Id
- 1894
- Evidence Id
- 1894
- Core Evidence Id
- 1894
- Source Clinical Trial Id
- 1869
- Herb2 Clinical Trial Id
- HBCT001869
- Nct Id
- NCT01864525
- Title
- Effects of Octanoic Acid for Treatment of Essential Voice Tremor
- Status
- Completed
- Phase
- Phase 1|Phase 2
- Study Result
- Yes
- Study Condition
- Essential Voice Tremor|Vocal Tremor|Voice Tremor|Essential Tremor of Voice
- Study Type
- Interventional
- Study Design
- Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
- Intervention
- DRUG: Octanoic acid|DRUG: Inactive capsule
- Intervention Allocation
- Randomized
- Intervention Model
- Crossover
- Intervention Mask
- Quadruple
- Intervention Purpose
- Treatment
- Gender
- All
- Age
- Adult, Older_Adult
- Enrollment
- 17
- Outcome Measure
- Magnitude of Acoustic Amplitude Tremor and Magnitude of Acoustic Frequency Tremor, Voice recordings were used to measure the degree of tremor in the voice. Mean post-test values for each acoustic measure were compared after the octanoic acid and placebo conditions, with and without consideration of baseline values. Mean values represent the average of two testing days. Degree of amplitude tremor shows the extent of amplitude variation as a percent of the mean signal amplitude, with lower numbers indicating less amplitude tremor. Baseline values for magnitude of amplitude tremor across all participants and conditions ranged from 4.06 to 27.09, and post-test values ranged from 1.94 to 26.02. Degree of frequency tremor shows the extent of fundamental frequency variation as a percent of the mean signal frequency, with lower numbers indicating less frequency tremor. Baseline values for magnitude of frequency tremor across all participants and conditions ranged from 1.21 to 15.31, and post-test values ranged from 0.60 to 13.86., Measured at baseline visits (1 & 2) and after 3 weeks of placebo or octanoic acid on post-test visits (1 & 2)
- Sponsor Collaborator
- Syracuse University|National Institute on Deafness and Other Communication Disorders (NIDCD)
- Funded By
- OTHER
- Location
- Syracuse University & Upstate Medical University, Syracuse, New York, 13210, United States
- Other Id
- 370955-3|1R03DC012429-01A1
- Start Date
- 2013-07
- Primary Completion Date
- 2016-12-22
- Completion Date
- 2017-03-31
- First Posted
- 2013-05-29
- Results First Posted
- 2018-08-20
- Last Update Posted
- 2018-08-20
- Study Document
- Study Url
- https://clinicaltrials.gov/study/NCT01864525
- Title Cn
- Title En
- Effects of Octanoic Acid for Treatment of Essential Voice Tremor
- Bilingual Status
- semi_complete