Clinical TrialID 1345
Effect of Intake of Allium Cepa L. Peel Heated Water Extract on Immunity Enhancement
NCT05666752
Upper Respiratory Infection
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Record Fields
Scalar fields from the final clinical_trial record.
- Clinical Trial Id
- 1345
- Evidence Id
- 1345
- Core Evidence Id
- 1345
- Source Clinical Trial Id
- 1323
- Herb2 Clinical Trial Id
- HBCT001323
- Nct Id
- NCT05666752
- Title
- Effect of Intake of Allium Cepa L. Peel Heated Water Extract on Immunity Enhancement
- Status
- Active_Not_Recruiting
- Phase
- Study Result
- No
- Study Condition
- Upper Respiratory Infection
- Study Type
- Interventional
- Study Design
- Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
- Intervention
- DIETARY_SUPPLEMENT: Allium Cepa L. Peel Heated Water Extract|DIETARY_SUPPLEMENT: Placebo
- Intervention Allocation
- Randomized
- Intervention Model
- Parallel
- Intervention Mask
- Double
- Intervention Purpose
- Prevention
- Gender
- All
- Age
- Adult, Older_Adult
- Enrollment
- 80
- Outcome Measure
- Changes of Natural killer(NK) cell activity, Changes of Natural killer(NK) cell activity will be assessed before and after the intervention. PBMCs were isolated by density gradient separation, resuspended in phosphate-buffered saline, and determined using trypan blue solution. Natural killer(NK) cell activity was calculated from the results of nonradioactive cytotoxicity assay kits. Effector cells (PBMCs) were seeded in 96-well plates, with 50 ul of target cells (K562), incubated for 4 hours. cytotoxicity was calculated using the following formula: \[(experimental-effector spontaneous-target spontaneous)/(target maximum-target spontaneous)\]\*100., At week 0 and week 8
- Sponsor Collaborator
- Hanyang University
- Funded By
- OTHER
- Location
- Hanyang University, Seoul, 04763, Korea, Republic of
- Other Id
- NAS-IE-ON
- Start Date
- 2022-11-07
- Primary Completion Date
- 2023-09
- Completion Date
- 2023-09
- First Posted
- 2022-12-28
- Results First Posted
- Last Update Posted
- 2022-12-28
- Study Document
- Study Url
- https://clinicaltrials.gov/study/NCT05666752
- Title Cn
- Title En
- Effect of Intake of Allium Cepa L. Peel Heated Water Extract on Immunity Enhancement
- Bilingual Status
- semi_complete