Clinical TrialID 1286
Effects of Oral Aloe Vera Juice on Chemotherapy and Radiation-induced Oral Mucositis and Esophagitis
NCT05369234
Oral Cavity Cancer|Head and Neck Cancers - Tonsils|Esophageal Cancer|Laryngeal Cancer|Oropharynx Cancer|Mediastinal Cancer|Chest Wall Tumor|Radiation Mucositis
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Record Fields
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- Clinical Trial Id
- 1286
- Evidence Id
- 1286
- Core Evidence Id
- 1286
- Source Clinical Trial Id
- 1268
- Herb2 Clinical Trial Id
- HBCT001268
- Nct Id
- NCT05369234
- Title
- Effects of Oral Aloe Vera Juice on Chemotherapy and Radiation-induced Oral Mucositis and Esophagitis
- Status
- Recruiting
- Phase
- Phase 3
- Study Result
- No
- Study Condition
- Oral Cavity Cancer|Head and Neck Cancers - Tonsils|Esophageal Cancer|Laryngeal Cancer|Oropharynx Cancer|Mediastinal Cancer|Chest Wall Tumor|Radiation Mucositis
- Study Type
- Interventional
- Study Design
- Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
- Intervention
- DIETARY_SUPPLEMENT: 100% Aloe Vera Juice|COMBINATION_PRODUCT: Magic Mouthwash|COMBINATION_PRODUCT: Salt and Baking soda rinse|DRUG: Carafate
- Intervention Allocation
- Randomized
- Intervention Model
- Parallel
- Intervention Mask
- Intervention Purpose
- Supportive_Care
- Gender
- All
- Age
- Adult, Older_Adult
- Enrollment
- 100
- Outcome Measure
- Prevention of Oral Mucositis and Esophagitis, to determine whether to add oral aloe vera juice to standard of care treatments for lip, oral cavity, hard palate, tongue, tonsil , pharyngeal, laryngeal, neck , esophageal, mediastinal, and chest wall cancers will help prevent oral mucositis and esophagitis symptoms while patients undergo radiation therapy. Symptoms will be assessed using the CTCAE v. 5.0 weekly while on treatment to determine if the addition of aloe vera juice impacts these symptoms when compared to subjects that don't receive aloe vera juice., 10 weeks|Management of Oral Mucositis and Esophagitis, to determine whether to add oral aloe vera juice to standard of care treatments for lip, oral cavity, hard palate, tongue, tonsil , pharyngeal, laryngeal, neck , esophageal, mediastinal, and chest wall cancers will help manage oral mucositis and esophagitis symptoms while patients undergo radiation therapy. Symptoms will be assessed using the CTCAE v. 5.0 weekly while on treatment to determine if the addition of aloe vera juice impacts these symptoms when compared to subjects that don't receive aloe vera juice., 10 weeks
- Sponsor Collaborator
- Thompson Cancer Survival Center
- Funded By
- OTHER
- Location
- Thompson Cancer Survival Center Radiation Oncology Services, Knoxville, Tennessee, 37916, United States
- Other Id
- 2022-404 INV Aloe_Oncology
- Start Date
- 2022-01-20
- Primary Completion Date
- 2024-01-30
- Completion Date
- 2024-01-30
- First Posted
- 2022-05-11
- Results First Posted
- Last Update Posted
- 2023-11-21
- Study Document
- Study Url
- https://clinicaltrials.gov/study/NCT05369234
- Title Cn
- Title En
- Effects of Oral Aloe Vera Juice on Chemotherapy and Radiation-induced Oral Mucositis and Esophagitis
- Bilingual Status
- semi_complete