Clinical TrialID 127
Effect of Gymnema Sylvestre on Metabolic Syndrome and Insulin
NCT02370121
Metabolic Syndrome
Relationship Network
Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.
Click a node to open it in a new tab
Trial: 1Herb: 1Links: 1
Arranging relationship network...
Record Fields
Scalar fields from the final clinical_trial record.
- Clinical Trial Id
- 127
- Evidence Id
- 127
- Core Evidence Id
- 127
- Source Clinical Trial Id
- 122
- Herb2 Clinical Trial Id
- HBCT000122
- Nct Id
- NCT02370121
- Title
- Effect of Gymnema Sylvestre on Metabolic Syndrome and Insulin
- Status
- Completed
- Phase
- Phase 2
- Study Result
- Yes
- Study Condition
- Metabolic Syndrome
- Study Type
- Interventional
- Study Design
- Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
- Intervention
- DRUG: Placebo|DRUG: Gymnema Sylvestre
- Intervention Allocation
- Randomized
- Intervention Model
- Parallel
- Intervention Mask
- Triple
- Intervention Purpose
- Treatment
- Gender
- All
- Age
- Adult
- Enrollment
- 24
- Outcome Measure
- Waist Circumference (WC), The WC was evaluated after an overnight fast with a flexible tape in the midpoint between the lowest rib and the iliac crest and is expressed in centimeters., Week 12|Triglycerides (TGs), The blood sample for determining of TGs, was taken after an overnight fast and was evaluated by spectrophotometry method. The value was expressed on mmol/L., week 12|High-density Lipoprotein Cholesterol (HDL-C), The blood sample for determining of HDL-C, was taken after an overnight fast and was evaluated by colorimetric method. The value was expressed on mmol/L., Week 12|Fasting Plasma Glucose (FPG), The blood sample for determining of FPG, was taken after an overnight fast and was evaluated by spectrophotometry method. The value was expressed on mmol/L., week 12|Systolic Blood Pressure (SBP), The SBP was evaluated with a digital sphygmomanometer with the subject sited down on a chair after a resting period of 5 minutes on three occasions. The mean of the three measures was considered as the value of SBP. The value was expressed on mmHg., week 12|Diastolic Blood Pressure (DBP), The DBP was evaluated with a digital sphygmomanometer with the subject sited down on a chair after a resting period of 5 minutes on three occasions. The mean of the three measures was considered as the value of DBP. The value was expressed on mmHg., week 12|Total Insulin Secretion, The total insulin secretion was calculated by the insulinogenic index (ΔABC insulin / ΔABC glucose)., Week 12|First Phase of Insulin Secretion, The first phase of insulin secretion was estimated using the Stumvoll index (1283+ 1.829 x insulin 30' - 138.7 x glucose 30' + 3.772 x insulin 0')., week 12|Insulin Sensitivity, The insulin sensitivity was calculated with Matsuda index \[10,000 / √glucose 0' x insulin 0') (mean glucose oral glucose tolerance test (OGTT) x mean insulin OGTT)\]., week 12
- Sponsor Collaborator
- University of Guadalajara
- Funded By
- OTHER
- Location
- Other Id
- CT-271281-YZ
- Start Date
- 2013-02
- Primary Completion Date
- 2014-12
- Completion Date
- 2015-01
- First Posted
- 2015-02-24
- Results First Posted
- 2016-06-03
- Last Update Posted
- 2019-06-18
- Study Document
- Study Url
- https://clinicaltrials.gov/study/NCT02370121
- Title Cn
- Title En
- Effect of Gymnema Sylvestre on Metabolic Syndrome and Insulin
- Bilingual Status
- semi_complete