Clinical TrialID 126
Effect of Gymnema Sylvestre on Patients With Impaired Glucose Tolerance.
NCT02708966
Impaired Glucose Tolerance
Relationship Network
Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.
Click a node to open it in a new tab
Trial: 1Herb: 1Links: 1
Arranging relationship network...
Record Fields
Scalar fields from the final clinical_trial record.
- Clinical Trial Id
- 126
- Evidence Id
- 126
- Core Evidence Id
- 126
- Source Clinical Trial Id
- 121
- Herb2 Clinical Trial Id
- HBCT000121
- Nct Id
- NCT02708966
- Title
- Effect of Gymnema Sylvestre on Patients With Impaired Glucose Tolerance.
- Status
- Completed
- Phase
- Phase 2
- Study Result
- Yes
- Study Condition
- Impaired Glucose Tolerance
- Study Type
- Interventional
- Study Design
- Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
- Intervention
- DRUG: Gymnema Sylvestre|DRUG: Placebo
- Intervention Allocation
- Randomized
- Intervention Model
- Parallel
- Intervention Mask
- Double
- Intervention Purpose
- Treatment
- Gender
- All
- Age
- Adult
- Enrollment
- 30
- Outcome Measure
- Fasting Plasma Glucose, After intervention by spectrophotometry, 90 days|2-hour Post Load Plasma Glucose (2-h PG), The blood sample for determining of 2-h PG, was taken two hours after the ingestion of the drink with 75 g dextrose and was evaluated by spectrophotometry method. The value was expressed on mmol/L., 90 days|Glycated Hemoglobin A1c (A1C), After intervention by high-performance liquid chromatography, 90 days|Total Insulin Secretion (Insulinogenic Index), Total insulin secretion was calculated with the insulinogenic index (ΔABC insulin / ΔABC glucose) after intervention., 90 days|First Phase of Insulin Secretion, First phase of insulin secretion was estimated using the Stumvoll index (1283+ 1.829 x insulin 30' - 138.7 x glucose 30' + 3.772 x insulin 0') after intervention., 90 days|Insulin Sensitivity (Matsuda Index), Insulin sensitivity was calculated with Matsuda index \[10,000 / √glucose 0' x insulin 0') (mean glucose oral glucose tolerance test (OGTT) x mean insulin OGTT)\] after intervention., 90 days
- Sponsor Collaborator
- University of Guadalajara
- Funded By
- OTHER
- Location
- Institute of Experimental and Clinical Therapeutics (INTEC), CUCS, University of Guadalajara, Guadalajara, Jalisco, 44340, Mexico
- Other Id
- GSIG
- Start Date
- 2016-03
- Primary Completion Date
- 2018-09
- Completion Date
- 2018-10
- First Posted
- 2016-03-15
- Results First Posted
- 2020-11-18
- Last Update Posted
- 2021-02-02
- Study Document
- Study Protocol, Statistical Analysis Plan, and Informed Consent Form, https://cdn.clinicaltrials.gov/large-docs/66/NCT02708966/Prot_SAP_ICF_000.pdf
- Study Url
- https://clinicaltrials.gov/study/NCT02708966
- Title Cn
- Title En
- Effect of Gymnema Sylvestre on Patients With Impaired Glucose Tolerance.
- Bilingual Status
- semi_complete