Clinical TrialID 123

Using MASL to Combat Oral Cancer

NCT04188665

Squamous Cell Carcinoma of Head and Neck

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Record Fields

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Clinical Trial Id
123
Evidence Id
123
Core Evidence Id
123
Source Clinical Trial Id
118
Herb2 Clinical Trial Id
HBCT000118
Nct Id
NCT04188665
Title
Using MASL to Combat Oral Cancer
Status
Recruiting
Phase
Early_Phase 1
Study Result
No
Study Condition
Squamous Cell Carcinoma of Head and Neck
Study Type
Interventional
Study Design
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Intervention
DRUG: MASL|OTHER: Placebo
Intervention Allocation
Randomized
Intervention Model
Parallel
Intervention Mask
Double
Intervention Purpose
Treatment
Gender
All
Age
Adult, Older_Adult
Enrollment
20
Outcome Measure
Pre-treatment OSCC morphology and PDPN expression, Measure morphology and podoplanin (PDPN) expression by immunohistochemistry of cells included in initial biopsies of oral lesions in comparison to normal oral squamous epithelial cells (OSCCs). We will select patients with lesions that express robust levels of PDPN and notable dysplasia for inclusion in the study., 1 day to 4 weeks.
Sponsor Collaborator
Rowan University|Rutgers University
Funded By
OTHER
Location
New Jersey Medical School, Newark, New Jersey, 07103, United States|Rutgers School for Dental Medicine, Newark, New Jersey, 07103, United States|University Hospital, Newark, New Jersey, 07103, United States|Rowan University, Stratford, New Jersey, 08084, United States
Other Id
Pro2019000548
Start Date
2021-01-29
Primary Completion Date
2024-12-31
Completion Date
2025-12-31
First Posted
2019-12-06
Results First Posted
Last Update Posted
2023-07-13
Study Document
Study Url
https://clinicaltrials.gov/study/NCT04188665
Title Cn
Title En
Using MASL to Combat Oral Cancer
Bilingual Status
semi_complete